Scientists suggest new strategy to inhibit untreatable, deadly nerve sheath...
Genomic profiling of mostly untreatable and deadly nerve sheath tumors led scientists to test a possible therapeutic strategy that inhibited tumor growth in lab tests on human tumor cells and mouse...
View ArticlePlymouth researcher receives grant to further investigate causes of...
The University of Plymouth will be continuing its research into the advancement of neuro-tumor treatments thanks to more than £100,000 from Great Ormond Street Hospital Children's Charity and Sparks,...
View ArticleFDA-approved drug for chemical abortion shows promise for treatment of...
Massachusetts Eye and Ear researchers have shown that mifepristone, a drug currently FDA-approved for chemical abortion, prevents the growth of vestibular schwannoma cells. This sometimes-lethal...
View ArticleResearchers show how Spred1 molecule protects HSC homeostasis under...
Researchers at Kanazawa University report in Cell Stem Cell how the Spred1 molecule is involved in hematopoietic stem cell self-renewal. Experiments with mouse models show that under normal conditions,...
View ArticleAuditory brainstem implant helps patients with neurofibromatosis type 2
Patients with rare brain tumors on the auditory nerve now have an option to prevent complete deafness at UC San Diego Health. The device, called an auditory brainstem implant or ABI, fits behind the...
View ArticleEMA grants orphan designation to selumetinib for treatment of...
AstraZeneca and Merck, known as MSD outside the U.S. and Canada, today announced that the European Medicines Agency (EMA) has granted orphan designation to selumetinib, a MEK 1/2 inhibitor, for the...
View ArticleRDMD raises $3 million in seed funding to accelerate rare disease research,...
RDMD, a healthcare technology company dedicated to accelerating research for patients with rare diseases, today announced that it has raised $3 million in seed financing.
View ArticleResearchers find how NF2 gene mutations lead to out-of-control cellular...
A team of Massachusetts General Hospital Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular...
View ArticleBeiGene collaborates with SpringWorks to evaluate new combinational therapy...
BeiGene, Ltd., a commercial-stage biopharmaceutical company focused on developing and commercializing innovative molecularly-targeted and immuno-oncology drugs for the treatment of cancer, and...
View ArticleResearch shows enlarged genotype-phenotype correlation for three-base pair...
International collaborative research led by Ludwine Messiaen, Ph.D., shows that while a three-base pair, in-frame deletion called p.Met992del in the NF1 gene has a mild phenotype for people with the...
View ArticleSlow-growing type of glioma may be vulnerable to immunotherapy, suggests study
Immunotherapy has proved effective in treating a number of cancers, but brain tumors have remained stubbornly resistant.
View ArticleCTF along with NTAP and Sage announce first-ever open data portal for...
The Children's Tumor Foundation, together with the Neurofibromatosis Therapeutic Acceleration Program and Sage Bionetworks, has announced the first-ever open data portal for scientific research results...
View ArticleScientists move one step closer towards treatment for low-grade gliomas with...
Treatment for low-grade gliomas in patients living with neurofibromatosis type 1 are now one step closer thanks to recent research discoveries initiated and funded by the Children's Tumor Foundation.
View ArticleMice sleeping fitfully help unravel mystery of insomnia
Mice that sleep fitfully could help researchers unravel the mystery of insomnia. Researchers at Washington University School of Medicine in St. Louis studied mice genetically modified to mimic the...
View ArticleRoyal Holloway professors to lead new to research into curing...
Linda Popplewell, Lecturer in Biomedical Sciences, and world-renowned Professor George Dickson, from the School of Biological Sciences, both at Royal Holloway, will lead a team looking for a treatment...
View ArticleResearch into cancer signaling network reveals new roadmap to tumor control
In this advanced age of molecular sleuthing, a research team led by Georgetown Lombardi Comprehensive Cancer Center have findings that suggest tumors will eventually become resistant to drug inhibitors...
View ArticleStudy discovers origin of neurofibromas that develop throughout the skin of...
A study published today in PLOS ONE discovered the origin of severely disfiguring masses of cells, called neurofibromas, that gradually develop throughout the skin of patients afflicted with...
View ArticleChildren's Tumor Foundation establishes significant research initiative to...
On the occasion of World NF2 Awareness Day, the Children's Tumor Foundation has announced the establishment of a significant research initiative dedicated to finding effective treatments for NF2, along...
View ArticleTargeting immune cells could potentially treat some kinds of brain tumor,...
Tumors arise when cells shake off their restraints and start to multiply out of control. But how fast a tumor grows does not depend solely on how quickly the cancer cells can divide, a new study has...
View ArticleResearchers open up possible avenue for new cancer treatments without side...
Researchers have opened up a possible avenue for new cancer therapies that don't have the side effects that oftentimes accompany many current cancer treatments by identifying a protein modification...
View Article